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tpmt.1


Official Full Name
thiopurine S-methyltransferase, tandem duplicate 1
Organism
Danio rerio
Gene ID
436842
Background
Predicted to enable thiopurine S-methyltransferase activity. Predicted to act upstream of or within methylation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; alopecia; leukopenia; and poor metabolism of thiopurines 1. Orthologous to human TPMT (thiopurine S-methyltransferase). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
tpmt; zgc:92752; zgc:109981; si:ch73-345a19.2

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