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TNNT1


Official Full Name
troponin T1, slow skeletal type
Organism
Homo sapiens
Gene ID
7138
Background
This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
ANM; TNT; NEM5; STNT; TNTS

Cat.No. Product Name Price
SHH432416 shRNA set against Human TNNT1 (NM_003283.4) Inquiry
SHH432420 shRNA set against Mouse TNNT1 (NM_011618.1) Inquiry
SHH432424 shRNA set against Rat TNNT1 (NM_134388.1) Inquiry
SHL086414 shRNA set against Rat Tnnt1(NM_134388.1) Inquiry
SHL086616 shRNA set against Mouse Tnnt1(NM_011618.1) Inquiry
SHW015512 shRNA set against Danio rerio TNNT1 (NM_181499) Inquiry
Cat.No. Product Name Price
CDFH020061 Human TNNT1 cDNA Clone(NM_001126132.1) Inquiry
CDFH020062 Human TNNT1 cDNA Clone(NM_001126133.1) Inquiry
CDFR014182 Rat Tnnt1 cDNA Clone(NM_134388.1) Inquiry
MiUTR1M-12024 TNNT1 miRNA 3'UTR clone Inquiry
MiUTR1R-08137 TNNT1 miRNA 3'UTR clone Inquiry
MiUTR3H-02295 TNNT1 miRNA 3'UTR clone Inquiry
MiUTR3H-02296 TNNT1 miRNA 3'UTR clone Inquiry
MiUTR3H-02297 TNNT1 miRNA 3'UTR clone Inquiry
CDCB176987 Danio rerio TNNT1 ORF Clone (NM_181499) Inquiry
CDCB181852 Rabbit TNNT1 ORF clone (XM_008253967.1) Inquiry
CDCH093734 human TNNT1 ORF clone (NM_003283.4) Inquiry
CDCH093736 human TNNT1 ORF clone (NM_001126133.1) Inquiry
CDCH093740 Mouse Tnnt1 ORF clone (NM_011618.1) Inquiry
CDCR348322 Human TNNT1 ORF Clone(NM_001126132.1) Inquiry
CDCR381207 Rat Tnnt1 ORF Clone(NM_134388.1) Inquiry
CDCS407753 Human TNNT1 ORF Clone (BC010963) Inquiry
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