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TNFSF12


Official Full Name
TNF superfamily member 12
Organism
Homo sapiens
Gene ID
8742
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
Synonyms
APO3L; DR3LG; TWEAK; TNLG4A

Cat.No. Product Name Price
SHH432112 shRNA set against Human TNFSF12 (NM_003809.2) Inquiry
SHH432116 shRNA set against Mouse TNFSF12 (NM_011614.3) Inquiry
SHH432120 shRNA set against Rat TNFSF12 (NM_001001513.2) Inquiry
SHL085508 shRNA set against Rat Tnfsf12(NM_001001513.2) Inquiry
SHL085544 shRNA set against Human TNFSF12(NM_003809.2) Inquiry
SHW010387 shRNA set against Danio rerio TNFSF12 (NM_001076607) Inquiry
Cat.No. Product Name Price
CDFH020020 Human TNFSF12 cDNA Clone(NM_003809.2) Inquiry
CDFR001168 Rat Tnfsf12 cDNA Clone(NM_001001513.2) Inquiry
MiUTR1H-10609 TNFSF12 miRNA 3'UTR clone Inquiry
MiUTR1R-08125 TNFSF12 miRNA 3'UTR clone Inquiry
CDCB156508 Canine TNFSF12 ORF clone (NM_001205168.1) Inquiry
CDCB156784 Cynomolgus TNFSF12 ORF clone Inquiry
CDCB157272 Mouse TNFSF12 ORF clone (NM_011614.1) Inquiry
CDCB171862 Danio rerio TNFSF12 ORF Clone (NM_001076607) Inquiry
CDCB183936 Rabbit TNFSF12 ORF clone (XM_008270779.1) Inquiry
CDCG002938 Mouse TNFSF12 ORF clone(NM_011614.3) Inquiry
CDCL186568 Human TNFSF12 ORF clone(NM_003809.2) Inquiry
CDCL186569 Rat TNFSF12 ORF clone(NM_001001513.2) Inquiry
CDCS411477 Human TNFSF12 ORF Clone (BC019047) Inquiry
CDCS411478 Human TNFSF12 ORF Clone (BC104420) Inquiry
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