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TNFRSF13B

Official Full Name
TNF receptor superfamily member 13B
Organism
Homo sapiens
GeneID
23495
Background
The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Synonyms
CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B;

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