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TNFRSF10A


Official Full Name
TNF receptor superfamily member 10a
Organism
Homo sapiens
Gene ID
8797
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Synonyms
DR4; APO2; CD261; TRAILR1; TRAILR-1

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