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TMX2

Official Full Name
thioredoxin related transmembrane protein 2
Organism
Homo sapiens
GeneID
51075
Background
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines. [provided by RefSeq, Jan 2017]
Synonyms
PIG26; CGI-31; PDIA12; NEDMCMS; TXNDC14;

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