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TMEM2


Official Full Name
cell migration inducing hyaluronidase 2
Organism
Homo sapiens
Gene ID
23670
Background
This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]
Synonyms
CEMIP2; TMEM2

Cat.No. Product Name Price
SHH429948 shRNA set against Human Tmem2 (NM_013390.2) Inquiry
SHH429952 shRNA set against Mouse Tmem2 (NM_031997.3) Inquiry
SHH429956 shRNA set against Rat Tmem2 (NM_001107596.1) Inquiry
SHL078582 shRNA set against Mouse Tmem2(NM_001033759.1) Inquiry
SHL078600 shRNA set against Mouse Tmem2(NM_031997.3) Inquiry
SHW011661 shRNA set against Danio rerio TMEM2 (NM_001099449) Inquiry
Cat.No. Product Name Price
CDCG002080 Human TMEM2 ORF clone(NM_013390.2) Inquiry
CDCH092436 human TMEM2 ORF clone (NM_001135820.1) Inquiry
CDFH019831 Human TMEM2 cDNA Clone(NM_001135820.1) Inquiry
CDFR007244 Rat Tmem2 cDNA Clone(NM_001107596.1) Inquiry
MiUTR1M-11893 TMEM2 miRNA 3'UTR clone Inquiry
MiUTR1M-11894 TMEM2 miRNA 3'UTR clone Inquiry
MiUTR3H-07996 TMEM2 miRNA 3'UTR clone Inquiry
MiUTR3H-07997 TMEM2 miRNA 3'UTR clone Inquiry
CDCB173136 Danio rerio TMEM2 ORF Clone (NM_001099449) Inquiry
CDCB191845 Rabbit TMEM2 ORF clone (XM_008256356.1) Inquiry
CDCH092438 Mouse Tmem2 ORF clone (NM_001033759.1) Inquiry
CDCR263992 Mouse Tmem2 ORF Clone(NM_031997.3) Inquiry
CDCR374331 Rat Tmem2 ORF Clone(NM_001107596.1) Inquiry
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