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TMED7-TICAM2

Official Full Name
TMED7-TICAM2 readthrough
Organism
Homo sapiens
GeneID
100302736
Background
This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. This fusion product functions to negatively regulate the adaptor MyD88-independent toll-like receptor 4 pathway. [provided by RefSeq, Nov 2010]
Synonyms
TIRP; TRAM; TICAM2; TIRAP3; MyD88-4; TICAM-2;

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