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TJP1


Official Full Name
tight junction protein 1
Organism
Homo sapiens
Gene ID
7082
Background
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
Synonyms
ZO-1

Cat.No. Product Name Price
SHH427672 shRNA set against Human TJP1 (NM_175610.2) Inquiry
SHH427680 shRNA set against Rat TJP1 (NM_001106266.1) Inquiry
SHL072102 shRNA set against Human TJP1(NM_003257.3) Inquiry
Cat.No. Product Name Price
CDFH019659 Human TJP1 cDNA Clone(NM_003257.3) Inquiry
CDFR006024 Rat Tjp1 cDNA Clone(NM_001106266.1) Inquiry
MiUTR1H-10424 TJP1 miRNA 3'UTR clone Inquiry
MiUTR1H-10425 TJP1 miRNA 3'UTR clone Inquiry
SKO0839 TJP1 Validated sgRNA vector Inquiry
CDCB189981 Rabbit TJP1 ORF clone (XM_008269782.1) Inquiry
CDCH091248 human TJP1 ORF clone (NM_175610.2) Inquiry
CDCR285236 Human TJP1 ORF Clone(NM_003257.3) Inquiry
CDCR373034 Rat Tjp1 ORF Clone(NM_001106266.1) Inquiry
CDCS411216 Human TJP1 ORF Clone (BC111712) Inquiry
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