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TIMP3

Official Full Name
TIMP metallopeptidase inhibitor 3
Organism
Homo sapiens
GeneID
7078
Background
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]
Synonyms
SFD; K222; K222TA2; HSMRK222;

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