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thraa


Official Full Name
thyroid hormone receptor alpha a
Organism
Danio rerio
Gene ID
30670
Background
Enables nuclear receptor activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including positive regulation of sarcomere organization; thyroid hormone receptor signaling pathway; and ventricular system development. Located in nucleus. Is expressed in several structures, including blastodisc; muscle; nervous system; optic cup; and pleuroperitoneal region. Used to study hypothyroidism. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 6 and renal cell carcinoma. Orthologous to human THRA (thyroid hormone receptor alpha). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
tra; thr1; thra; tra1; nr1a1; thral; TR[a]1; wu:fb59g07

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SHW014856 shRNA set against Danio rerio THRAA (NM_131396) Inquiry
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CDCB176331 Danio rerio THRAA ORF Clone (NM_131396) Inquiry
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