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THOP1

Official Full Name
thimet oligopeptidase 1
Organism
Homo sapiens
GeneID
7064
Background
The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015]
Synonyms
TOP; MP78; EP24.15; MEPD_HUMAN;

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