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tgfbr1a

Official Full Name
transforming growth factor, beta receptor 1 a
Organism
Danio rerio
GeneID
560578
Background
Predicted to enable SMAD binding activity; activin binding activity; and transmembrane receptor protein serine/threonine kinase activity. Involved in vascular endothelial cell proliferation. Predicted to be located in bicellular tight junction; cell surface; and membrane raft. Predicted to be part of activin receptor complex. Predicted to be active in plasma membrane. Is expressed in brain; endoderm; eye; heart; and pharyngeal arch. Human ortholog(s) of this gene implicated in Loeys-Dietz syndrome 1; Lynch syndrome; carcinoma (multiple); colorectal cancer; and urinary bladder cancer. Orthologous to human TGFBR1 (transforming growth factor beta receptor 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
tgfbr1; zgc:123263;

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