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tdo2b


Official Full Name
tryptophan 2,3-dioxygenase b
Organism
Danio rerio
Gene ID
334082
Background
Predicted to enable heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in protein homotetramerization; tryptophan catabolic process to acetyl-CoA; and tryptophan catabolic process to kynurenine. Predicted to act upstream of or within tryptophan catabolic process. Is expressed in gut and liver. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Orthologous to human TDO2 (tryptophan 2,3-dioxygenase). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Tdo2; tdo2l; fi30d08; zgc:63488; wu:fi30d08

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