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tdo2a

Official Full Name
tryptophan 2,3-dioxygenase a
Organism
Danio rerio
GeneID
100008541
Background
Predicted to enable heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in protein homotetramerization; tryptophan catabolic process to acetyl-CoA; and tryptophan catabolic process to kynurenine. Predicted to act upstream of or within tryptophan catabolic process. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Orthologous to human TDO2 (tryptophan 2,3-dioxygenase). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
tdo2; fb62b10; wu:fb62b10; zgc:103693;

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