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tdgf1

Official Full Name
teratocarcinoma-derived growth factor 1
Organism
Danio rerio
GeneID
30304
Background
Predicted to enable activin receptor binding activity and nodal binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; nervous system development; and regionalization. Located in external side of plasma membrane. Is expressed in several structures, including EVL; cardiovascular system; diencephalon; ectoderm; and mesoderm. Used to study neural tube defect. Human ortholog(s) of this gene implicated in colon cancer and congenital heart disease. Orthologous to several human genes including CRIPTO (cripto, EGF-CFC family member). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
oep; cb85; cripto; wu:fe01d04; zgc:109829;

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