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TCF7


Official Full Name
transcription factor 7
Organism
Homo sapiens
Gene ID
6932
Background
This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling. [provided by RefSeq, Oct 2016]
Synonyms
TCF-1

Cat.No. Product Name Price
SHH424856 shRNA set against Human TCF7 (NM_003202.3) Inquiry
SHH424860 shRNA set against Mouse TCF7 (NM_009331.3) Inquiry
SHW005059 shRNA set against Chicken TCF7 (NM_204547) Inquiry
SHW007929 shRNA set against Danio rerio TCF7 (NM_001012389) Inquiry
Cat.No. Product Name Price
CDCH089726 human TCF7 ORF clone (NM_201634.3) Inquiry
CDCR327113 Human TCF7 ORF Clone(NM_201632.3) Inquiry
MiUTR1M-11623 TCF7 miRNA 3'UTR clone Inquiry
MiUTR3H-02240 TCF7 miRNA 3'UTR clone Inquiry
MiUTR3H-02241 TCF7 miRNA 3'UTR clone Inquiry
MiUTR3H-02242 TCF7 miRNA 3'UTR clone Inquiry
MiUTR4H-TG08847 TCF7 miRNA 3'UTR clone Inquiry
CDCB166534 Chicken TCF7 ORF Clone (NM_204547) Inquiry
CDCB169404 Danio rerio TCF7 ORF Clone (NM_001012389) Inquiry
CDCB194104 Rabbit TCF7 ORF clone (XM_008255007.1) Inquiry
CDCR247036 Mouse Tcf7 ORF Clone(NM_009331.3) Inquiry
CDCR328357 Human TCF7 ORF Clone(NM_213648.3) Inquiry
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