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tbx2b


Official Full Name
T-box transcription factor 2b
Organism
Danio rerio
Gene ID
30253
Background
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in BMP signaling pathway. Acts upstream of or within several processes, including heart development; nephron tubule development; and nervous system development. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including heart; immature eye; mesoderm; nervous system; and pronephros. Human ortholog(s) of this gene implicated in atrial heart septal defect; heart septal defect; and vertebral anomalies and variable endocrine and T-cell dysfunction. Orthologous to human TBX2 (T-box transcription factor 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
tbx2; tbxc; tbx-c; zeh1581; hm:zeh1581

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