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TBX1


Official Full Name
T-box transcription factor 1
Organism
Homo sapiens
Gene ID
6899
Background
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Synonyms
DGS; TGA; VCF; CAFS; CTHM; DGCR; DORV; VCFS; TBX1C; CATCH22

Cat.No. Product Name Price
SHG171393 shRNA set against Human TBX1(NM_005992.1) Inquiry
SHG171285 shRNA set against Human TBX1(NM_080647.1) Inquiry
SHG171425 shRNA set against Human TBX1(NM_080647.1) Inquiry
SHG171439 shRNA set against Human TBX1(NM_080646.1) Inquiry
SHH424336 shRNA set against Human TBX1 (NM_005992.1) Inquiry
SHH424340 shRNA set against Mouse TBX1 (NM_011532.1) Inquiry
SHH424344 shRNA set against Rat TBX1 (NM_001108322.1) Inquiry
SHL059858 shRNA set against Mouse Tbx1(NM_011532.1) Inquiry
SHW015585 shRNA set against Danio rerio TBX1 (NM_183339) Inquiry
Cat.No. Product Name Price
CDFG007376 Human TBX1 cDNA Clone(NM_080646.1) Inquiry
CDFG007377 Human TBX1 cDNA Clone(NM_080647.1) Inquiry
CDFH019292 Human TBX1 cDNA Clone(NM_005992.1) Inquiry
CDFR007960 Rat Tbx1 cDNA Clone(NM_001108322.1) Inquiry
MiUTR1H-10239 TBX1 miRNA 3'UTR clone Inquiry
MiUTR1H-10240 TBX1 miRNA 3'UTR clone Inquiry
MiUTR1H-10241 TBX1 miRNA 3'UTR clone Inquiry
MiUTR1M-11592 TBX1 miRNA 3'UTR clone Inquiry
CDCB177060 Danio rerio TBX1 ORF Clone (NM_183339) Inquiry
CDCB184838 Rabbit TBX1 ORF clone (XM_008250593.1) Inquiry
CDCH089440 Mouse Tbx1 ORF clone (NM_011532.1) Inquiry
CDCR051568 Human TBX1 ORF clone (NM_005992.1) Inquiry
CDCR051570 Human TBX1 ORF clone (NM_080646.1) Inquiry
CDCR315108 Human TBX1 ORF Clone(NM_080647.1) Inquiry
CDCR374829 Rat Tbx1 ORF Clone(NM_001108322.1) Inquiry
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