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TBN

Official Full Name
TATA-box binding protein associated factor 8
Organism
Homo sapiens
GeneID
129685
Background
This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Synonyms
TAF8; II; TAF; TBN; NEDMLHB; TAFII43; TAFII-43; TAF(II)43;

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