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TAF1B

Official Full Name
TATA-box binding protein associated factor, RNA polymerase I subunit B
Organism
Homo sapiens
GeneID
9014
Background
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Synonyms
SL1; RAF1B; RAFI63; TAFI63; MGC:9349;

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