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T

Official Full Name
brachyury, T-box transcription factor T
Organism
Mus musculus
GeneID
20997
Background
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in cardiac muscle cell myoblast differentiation and regulation of DNA-templated transcription. Acts upstream of or within several processes, including chordate embryonic development; circulatory system development; and embryonic morphogenesis. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including egg cylinder; embryo mesenchyme; future spinal cord; genitourinary system; and mesoderm. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human TBXT (T-box transcription factor T). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
T; Lr; T1; Bra; Low; Tl2; Tl3; cou; Tbxt; me75; D17Mit170;

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