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STAT5B


Official Full Name
signal transducer and activator of transcription 5B
Organism
Homo sapiens
Gene ID
6777
Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
Synonyms
STAT5; GHISID2

Cat.No. Product Name Price
SHH419444 shRNA set against Human STAT5B (NM_012448.3) Inquiry
SHH419448 shRNA set against Mouse STAT5B (NM_011489.3) Inquiry
SHH419452 shRNA set against Rat STAT5B (NM_022380.1) Inquiry
SHL040350 shRNA set against Human STAT5B(NM_012448.3) Inquiry
SHL040418 shRNA set against Rat Stat5b(NM_022380.1) Inquiry
SHL040436 shRNA set against Mouse Stat5b(NM_011489.3) Inquiry
SHW005286 shRNA set against Chicken STAT5B (NM_204779) Inquiry
SHW007069 shRNA set against Danio rerio STAT5B (NM_001003984) Inquiry
Cat.No. Product Name Price
CDFH018794 Human STAT5B cDNA Clone(NM_012448.3) Inquiry
CDFR011985 Rat Stat5b cDNA Clone(NM_022380.1) Inquiry
MiUTR1H-09982 STAT5B miRNA 3'UTR clone Inquiry
MiUTR1M-11315 STAT5B miRNA 3'UTR clone Inquiry
CDCB166761 Chicken STAT5B ORF Clone (NM_204779) Inquiry
CDCB168544 Danio rerio STAT5B ORF Clone (NM_001003984) Inquiry
CDCB188868 Rabbit STAT5B ORF clone (XM_002719393.2) Inquiry
CDCR236976 Mouse Stat5b ORF Clone(NM_001113563.1) Inquiry
CDCR250807 Mouse Stat5b ORF Clone(NM_011489.3) Inquiry
CDCR296084 Human STAT5B ORF Clone(NM_012448.3) Inquiry
CDCR378988 Rat Stat5b ORF Clone(NM_022380.1) Inquiry
CDCS413340 Human STAT5B ORF Clone (BC020868) Inquiry
Cat.No. Product Name Price
CC-1357 STAT5B Easy KO Kit Inquiry
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