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SPRY2


Official Full Name
sprouty RTK signaling antagonist 2
Organism
Homo sapiens
Gene ID
10253
Background
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008]
Synonyms
IGAN3; hSPRY2

Cat.No. Product Name Price
SHH417356 shRNA set against Human SPRY2 (NM_005842.2) Inquiry
SHH417360 shRNA set against Mouse SPRY2 (NM_011897.3) Inquiry
SHH417364 shRNA set against Rat SPRY2 (NM_001012046.1) Inquiry
SHL031148 shRNA set against Rat Spry2(NM_001012046.1) Inquiry
SHL031184 shRNA set against Human SPRY2(NM_005842.2) Inquiry
SHL031202 shRNA set against Mouse Spry2(NM_011897.3) Inquiry
SHW005306 shRNA set against Chicken SPRY2 (NM_204800) Inquiry
SHW007017 shRNA set against Danio rerio SPRY2 (NM_001003842) Inquiry
Cat.No. Product Name Price
CDCS412449 Human SPRY2 ORF Clone (BC015745) Inquiry
CDFH018568 Human SPRY2 cDNA Clone(NM_005842.2) Inquiry
CDFR002474 Rat Spry2 cDNA Clone(NM_001012046.1) Inquiry
MiUTR1H-09878 SPRY2 miRNA 3'UTR clone Inquiry
MiUTR1M-11203 SPRY2 miRNA 3'UTR clone Inquiry
MiUTR1R-07674 SPRY2 miRNA 3'UTR clone Inquiry
CDCB158933 Human SPRY2 ORF clone (BC015745) Inquiry
CDCB166781 Chicken SPRY2 ORF Clone (NM_204800) Inquiry
CDCB168492 Danio rerio SPRY2 ORF Clone (NM_001003842) Inquiry
CDCB186583 Rabbit SPRY2 ORF clone (XM_008260093.1) Inquiry
CDCR251540 Mouse Spry2 ORF Clone(NM_011897.3) Inquiry
CDCR291426 Human SPRY2 ORF Clone(NM_005842.2) Inquiry
CDCR369521 Rat Spry2 ORF Clone(NM_001012046.1) Inquiry
CDCS412450 Human SPRY2 ORF Clone (BC004205) Inquiry
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