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Spnb2

Official Full Name
spectrin beta, non-erythrocytic 1
Organism
Mus musculus
GeneID
20742
Background
Predicted to enable GTPase binding activity; actin filament binding activity; and ankyrin binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in central nervous system formation and protein localization to plasma membrane. Acts upstream of or within regulation of SMAD protein signal transduction. Located in several cellular components, including M band; axolemma; and cuticular plate. Is expressed in heart; liver; lung; nervous system; and spleen. Used to study Beckwith-Wiedemann syndrome. Orthologous to human SPTBN1 (spectrin beta, non-erythrocytic 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Sptbn1; elf1; elf3; SPTB2; Spnb2; Spnb-2; mKIAA4049; 9930031C03Rik;

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