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Spnb1

Official Full Name
spectrin beta, erythrocytic
Organism
Mus musculus
GeneID
20741
Background
Enables actin filament binding activity. Acts upstream of or within hemopoiesis; plasma membrane organization; and porphyrin-containing compound biosynthetic process. Located in cortical cytoskeleton; plasma membrane; and spectrin-associated cytoskeleton. Is expressed in brain; liver; and spleen. Human ortholog(s) of this gene implicated in hereditary spherocytosis and hereditary spherocytosis type 2. Orthologous to human SPTB (spectrin beta, erythrocytic). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Sptb; ja; Spnb1; Gm1301; Spnb-1; jaundiced; mKIAA4219; D330027P03Rik;

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