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SOSTDC1

Official Full Name
sclerostin domain containing 1
Organism
Homo sapiens
GeneID
25928
Background
This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]
Synonyms
DAND7; USAG1; CDA019; ECTODIN;

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