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SNF8

Official Full Name
SNF8 subunit of ESCRT-II
Organism
Homo sapiens
GeneID
11267
Background
The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Synonyms
Dot3; EAP30; NEDOA; VPS22; DEE115;

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