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SMCR8

Official Full Name
SMCR8-C9orf72 complex subunit
Organism
Homo sapiens
GeneID
140775
Background
Enables GTPase activator activity; protein kinase binding activity; and protein kinase inhibitor activity. Contributes to guanyl-nucleotide exchange factor activity. Involved in negative regulation of gene expression; regulation of TOR signaling; and regulation of macroautophagy. Located in Atg1/ULK1 kinase complex; chromatin; and nucleoplasm. Part of guanyl-nucleotide exchange factor complex. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
DENND8A;

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