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Slc34A1


Official Full Name
solute carrier family 34 (sodium phosphate), member 1
Organism
Mus musculus
Gene ID
20505
Background
Enables sodium:phosphate symporter activity. Involved in several processes, including inorganic diphosphate transport; phosphate ion homeostasis; and response to sodium phosphate. Acts upstream of or within bone remodeling. Located in apical plasma membrane; basolateral plasma membrane; and vesicle. Is expressed in genitourinary system; ileum; skeleton; and tooth. Used to study hereditary hypophosphatemic rickets with hypercalciuria. Human ortholog(s) of this gene implicated in several diseases, including Fanconi syndrome (multiple); chronic kidney disease; hereditary hypophosphatemic rickets with hypercalciuria; hypophosphatemic nephrolithiasis/osteoporosis 1; and nephrolithiasis. Orthologous to human SLC34A1 (solute carrier family 34 member 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Slc34a1; Npt2; Npt2a; Slc17a2; NaPi-IIa

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