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SLC1A1

Official Full Name
solute carrier family 1 member 1
Organism
Homo sapiens
GeneID
6505
Background
This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010]
Synonyms
DCBXA; EAAC1; EAAT3; SCZD18; hEAAC1;

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