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SKIV2L2

Official Full Name
Mtr4 exosome RNA helicase
Organism
Homo sapiens
GeneID
23517
Background
Enables ATP binding activity and RNA helicase activity. Involved in DNA damage response; RNA catabolic process; and maturation of 5.8S rRNA. Located in nuclear exosome (RNase complex) and nucleoplasm. Part of TRAMP complex and catalytic step 2 spliceosome. Biomarker of amyotrophic lateral sclerosis. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
MTREX; Dob1; Mtr4; SKIV2L2; fSAP118; KIAA0052;

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