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SERPINF2

Official Full Name
serpin family F member 2
Organism
Homo sapiens
GeneID
5345
Background
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Synonyms
AAP; API; PLI; A2AP; alpha2AP; ALPHA-2-PI;

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