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SERPINF1

Official Full Name
serpin family F member 1
Organism
Homo sapiens
GeneID
5176
Background
This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016]
Synonyms
OI6; OI12; PEDF; EPC-1; PIG35;

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