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SZT2

Official Full Name
SZT2 subunit of KICSTOR complex
Organism
Homo sapiens
GeneID
23334
Background
The protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. [provided by RefSeq, Jun 2011]
Synonyms
DEE18; KICS1; SZT2A; SZT2B; EIEE18; C1orf84; KIAA0467;

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