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SVIL


Official Full Name
supervillin
Organism
Homo sapiens
Gene ID
6840
Background
This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Several transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Apr 2016]
Synonyms
MFM10

Cat.No. Product Name Price
SHH421320 shRNA set against Human SVIL (NM_003174.3) Inquiry
SHH421324 shRNA set against Mouse SVIL (NM_153153.3) Inquiry
SHH421328 shRNA set against Rat SVIL (NM_001108416.2) Inquiry
SHL049212 shRNA set against Human SVIL(NM_021738.2) Inquiry
SHL049266 shRNA set against Human SVIL(NM_003174.3) Inquiry
Cat.No. Product Name Price
CDFL013307 Mouse Svil cDNA Clone(NM_153153.3) Inquiry
MiUTR1H-10094 SVIL miRNA 3'UTR clone Inquiry
MiUTR1H-10095 SVIL miRNA 3'UTR clone Inquiry
CDCB185300 Rabbit SVIL ORF clone (XM_008268018.1) Inquiry
CDCR270212 Mouse Svil ORF Clone(NM_153153.3) Inquiry
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