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SUV39H1


Official Full Name
SUV39H1 histone lysine methyltransferase
Organism
Homo sapiens
Gene ID
6839
Background
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Synonyms
MG44; KMT1A; SUV39H; H3-K9-HMTase 1

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