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SUMF1

Official Full Name
sulfatase modifying factor 1
Organism
Homo sapiens
GeneID
285362
Background
This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Synonyms
FGE; UNQ3037; AAPA3037;

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