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SUCLG1

Official Full Name
succinate-CoA ligase GDP/ADP-forming subunit alpha
Organism
Homo sapiens
GeneID
8802
Background
This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq, Feb 2010]
Synonyms
GALPHA; MTDPS9; SUCLA1;

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