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STRADA


Official Full Name
STE20 related adaptor alpha
Organism
Homo sapiens
Gene ID
92335
Background
The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq, Sep 2009]
Synonyms
LYK5; PMSE; Stlk; STRAD; NY-BR-96; STRAD alpha

Cat.No. Product Name Price
SHH420104 shRNA set against Human STRADA (NM_153335.5) Inquiry
SHH420108 shRNA set against Mouse STRADA (NM_028126.3) Inquiry
SHH420112 shRNA set against Rat STRADA (NM_182820.1) Inquiry
SHW001010 shRNA set against Chicken STRADA (NM_001012844) Inquiry
SHW016166 shRNA set against Danio rerio STRADA (NM_199911) Inquiry
Cat.No. Product Name Price
CDCB156205 Rat STRADA ORF clone (BC081911.1) Inquiry
MiUTR3H-10122 STRADA miRNA 3'UTR clone Inquiry
MiUTR3H-10121 STRADA miRNA 3'UTR clone Inquiry
MiUTR3H-10120 STRADA miRNA 3'UTR clone Inquiry
MiUTR3H-10119 STRADA miRNA 3'UTR clone Inquiry
MiUTR3H-10118 STRADA miRNA 3'UTR clone Inquiry
CDFR015078 Rat Strada cDNA Clone(NM_182820.1) Inquiry
CDFH018889 Human STRADA cDNA Clone(NM_001165970.1) Inquiry
CDFH018888 Human STRADA cDNA Clone(NM_001165969.1) Inquiry
MiUTR3H-10123 STRADA miRNA 3'UTR clone Inquiry
CDCR382079 Rat Strada ORF Clone(NM_182820.1) Inquiry
CDCH402728 Mouse STRADA ORF clone(NM_028126.3) Inquiry
SKO0818 STRADA Validated sgRNA vector Inquiry
CDCL150260 Human STRADA ORF clone (NM_001165969.1) Inquiry
CDCS406178 Human STRADA ORF Clone (BC043641) Inquiry
CDCL150258 Human STRADA ORF clone (NM_153335.5) Inquiry
CDCL150256 Human STRADA ORF clone (NM_001003787.2) Inquiry
CDCH402729 Mouse STRADA ORF clone(NM_001252449.1) Inquiry
CDCH402727 Mouse STRADA ORF clone(NM_001252448.1) Inquiry
CDCB188679 Rabbit STRADA ORF clone (XM_008271694.1) Inquiry
CDCB177641 Danio rerio STRADA ORF Clone (NM_199911) Inquiry
CDCB162485 Chicken STRADA ORF Clone (NM_001012844) Inquiry
CDCL150262 Human STRADA ORF clone (NM_001165970.1) Inquiry
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