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STIL


Official Full Name
STIL centriolar assembly protein
Organism
Homo sapiens
Gene ID
6491
Background
This gene encodes a cytoplasmic protein implicated in regulation of the mitotic spindle checkpoint, a regulatory pathway that monitors chromosome segregation during cell division to ensure the proper distribution of chromosomes to daughter cells. The protein is phosphorylated in mitosis and in response to activation of the spindle checkpoint, and disappears when cells transition to G1 phase. It interacts with a mitotic regulator, and its expression is required to efficiently activate the spindle checkpoint. It is proposed to regulate Cdc2 kinase activity during spindle checkpoint arrest. Chromosomal deletions that fuse this gene and the adjacent locus commonly occur in T cell leukemias, and are thought to arise through illegitimate V-(D)-J recombination events. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
SIL; MCPH7

Cat.No. Product Name Price
SHH419628 shRNA set against Human STIL (NM_003035.2) Inquiry
SHH419632 shRNA set against Mouse STIL (NM_009185.3) Inquiry
SHL033558 shRNA set against Human STIL(NM_001048166.1) Inquiry
SHL033778 shRNA set against Mouse Stil(NM_009185.3) Inquiry
SHL033808 shRNA set against Human STIL(NM_003035.2) Inquiry
SHW015404 shRNA set against Danio rerio STIL (NM_173244) Inquiry
Cat.No. Product Name Price
CDFH018826 Human STIL cDNA Clone(NM_001048166.1) Inquiry
MiUTR1H-09997 STIL miRNA 3'UTR clone Inquiry
MiUTR1H-09998 STIL miRNA 3'UTR clone Inquiry
MiUTR1M-11328 STIL miRNA 3'UTR clone Inquiry
CDCB176879 Danio rerio STIL ORF Clone (NM_173244) Inquiry
CDCB194864 Rabbit STIL ORF clone (XM_008265287.1) Inquiry
CDCH086826 human STIL ORF clone (NM_001048166.1) Inquiry
CDCH086828 human STIL ORF clone (NM_003035.2) Inquiry
CDCR246723 Mouse Stil ORF Clone(NM_009185.3) Inquiry
CDCS407156 Human STIL ORF Clone (BC126223) Inquiry
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