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STAT6


Official Full Name
signal transducer and activator of transcription 6
Organism
Homo sapiens
Gene ID
6778
Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Synonyms
HIES6; STAT6B; STAT6C; D12S1644; IL-4-STAT

Cat.No. Product Name Price
SHH419464 shRNA set against Rat STAT6 (NM_001044250.1) Inquiry
SHL040602 shRNA set against Mouse Stat6(NM_009284.2) Inquiry
SHH419456 shRNA set against Human STAT6 (NM_003153.4) Inquiry
SHH419460 shRNA set against Mouse STAT6 (NM_009284.2) Inquiry
SHW012960 shRNA set against Danio rerio STAT6 (NM_001130590) Inquiry
Cat.No. Product Name Price
SKO1108 STAT6 Validated sgRNA vector Inquiry
MiUTR1R-07735 STAT6 miRNA 3'UTR clone Inquiry
MiUTR1M-11316 STAT6 miRNA 3'UTR clone Inquiry
CDFR004775 Rat Stat6 cDNA Clone(NM_001044250.1) Inquiry
CDFH018798 Human STAT6 cDNA Clone(NM_001178080.1) Inquiry
CDFH018797 Human STAT6 cDNA Clone(NM_001178081.1) Inquiry
CDCR357268 Human STAT6 ORF Clone(NM_001178079.1) Inquiry
CDFH018796 Human STAT6 cDNA Clone(NM_001178079.1) Inquiry
CDCR371488 Rat Stat6 ORF Clone(NM_001044250.1) Inquiry
MiUTR3H-04171 STAT6 miRNA 3'UTR clone Inquiry
CDFH018795 Human STAT6 cDNA Clone(NM_001178078.1) Inquiry
CDCS409101 Human STAT6 ORF Clone (BC075852) Inquiry
CDCR357266 Human STAT6 ORF Clone(NM_001178078.1) Inquiry
CDCH086722 Mouse Stat6 ORF clone (NM_009284.2) Inquiry
CDCH086716 human STAT6 ORF clone (NM_001178080.1) Inquiry
CDCB191171 Rabbit STAT6 ORF clone (XM_008274198.1) Inquiry
CDCB174435 Danio rerio STAT6 ORF Clone (NM_001130590) Inquiry
CDCR357272 Human STAT6 ORF Clone(NM_001178081.1) Inquiry
CDCB159598 Human STAT6 ORF clone (BC075852) Inquiry
Cat.No. Product Name Price
CC-1358 STAT6 Easy KO Kit Inquiry
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