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stat1a

Official Full Name
signal transducer and activator of transcription 1a
Organism
Danio rerio
GeneID
30768
Background
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; regulation of transcription by RNA polymerase II; and response to peptide hormone. Predicted to act upstream of or within regulation of DNA-templated transcription and signal transduction. Predicted to be part of ISGF3 complex. Predicted to be active in cytoplasm and nucleus. Is expressed in blood; kidney; retina; spleen; and telencephalon. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple); breast cancer (multiple); immunodeficiency 31A; immunodeficiency 31B; and immunodeficiency 31C. Orthologous to human STAT1 (signal transducer and activator of transcription 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
stat1;

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