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STAP1


Official Full Name
signal transducing adaptor family member 1
Organism
Homo sapiens
Gene ID
26228
Background
The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Synonyms
BRDG1; STAP-1

Cat.No. Product Name Price
SHH419228 shRNA set against Human STAP1 (NM_012108.2) Inquiry
SHH419232 shRNA set against Mouse STAP1 (NM_019992.3) Inquiry
SHH419236 shRNA set against Rat STAP1 (NM_001025115.1) Inquiry
Cat.No. Product Name Price
CDFL013151 Mouse Stap1 cDNA Clone(NM_019992.3) Inquiry
CDFR003845 Rat Stap1 cDNA Clone(NM_001025115.1) Inquiry
MiUTR1H-00942 STAP1 miRNA 3'UTR clone Inquiry
MiUTR1M-01329 STAP1 miRNA 3'UTR clone Inquiry
MiUTR1R-06799 STAP1 miRNA 3'UTR clone Inquiry
CDCB183825 Rabbit STAP1 ORF clone (XM_008267803.1) Inquiry
CDCL186319 Human STAP1 ORF clone(NM_012108.2) Inquiry
CDCR254623 Mouse Stap1 ORF Clone(NM_019992.3) Inquiry
CDCR370867 Rat Stap1 ORF Clone(NM_001025115.1) Inquiry
CDCS413203 Human STAP1 ORF Clone (BC014958) Inquiry
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