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ST8SIA1

Official Full Name
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Organism
Homo sapiens
GeneID
6489
Background
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]
Synonyms
GD3S; SIAT8; SIAT8A; SIAT8-A; ST8SiaI;

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