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SRGAP2

Official Full Name
SLIT-ROBO Rho GTPase activating protein 2
Organism
Homo sapiens
GeneID
23380
Background
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014]
Synonyms
FNBP2; SRGAP3; SRGAP2A; ARHGAP34;

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