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SPSB3

Official Full Name
splA/ryanodine receptor domain and SOCS box containing 3
Organism
Homo sapiens
GeneID
90864
Background
Enables ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including negative regulation of cGAS/STING signaling pathway; negative regulation of epithelial to mesenchymal transition; and protein K48-linked ubiquitination. Part of Cul5-RING ubiquitin ligase complex. Is active in nucleus. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
SSB3; C16orf31;

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