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SPECC1L

Official Full Name
sperm antigen with calponin homology and coiled-coil domains 1 like
Organism
Homo sapiens
GeneID
23384
Background
This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]
Synonyms
TBHS; CYTSA; GBBB2; TBHS1; OBLFC1;

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