Pages
Products

SPANXB1


Official Full Name
SPANX family member B1
Organism
Homo sapiens
Gene ID
728695
Background
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular family member contains an additional 18 nucleotides in its coding region compared to the other family members in the same gene cluster. This family member is also subject to gene copy number variation. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq, Apr 2014]
Synonyms
B1; CT11.2; SPANXB; SPANX-B; SPANXB2; SPANXF1; SPANXF2

Cat.No. Product Name Price
SHH415928 shRNA set against Human SPANXB1 (NM_032461.2) Inquiry
Cat.No. Product Name Price
CDFG006137 Human SPANXB1 cDNA Clone(NM_032461.2) Inquiry
MiUTR1H-09803 SPANXB1 miRNA 3'UTR clone Inquiry
CDCR312384 Human SPANXB1 ORF Clone(NM_032461.2) Inquiry
Quick Inquiry