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SPACA1


Official Full Name
sperm acrosome associated 1
Organism
Homo sapiens
Gene ID
81833
Background
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. [provided by RefSeq, Jul 2008]
Synonyms
SAMP32; SPGF85

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SHH415708 shRNA set against Human SPACA1 (NM_030960.2) Inquiry
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SHL025200 shRNA set against Human SPACA1(NM_030960.2) Inquiry
Cat.No. Product Name Price
CDFG005285 Human SPACA1 cDNA Clone(NM_030960.2) Inquiry
MiUTR1H-09783 SPACA1 miRNA 3'UTR clone Inquiry
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CDCB193898 Rabbit SPACA1 ORF clone (XM_008263197.1) Inquiry
CDCH402024 Rat SPACA1 ORF clone(NM_001191982.1) Inquiry
CDCR258459 Mouse Spaca1 ORF Clone(NM_026293.3) Inquiry
CDCR310920 Human SPACA1 ORF Clone(NM_030960.2) Inquiry
CDCS416048 Human SPACA1 ORF Clone (BC029488) Inquiry
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